Antioxidant and Cytoprotective Effects of Herbal Extract-Enriched Artificial Saliva: In-Vitro Biocompatibility and Cell Culture Studies.

The antioxidant activity of the artificial saliva formulations was assessed using the DPPH radical scavenging assay. Quantitative results are presented in Fig 11. Formulations containing plant extracts demonstrated statistically significantly higher radical scavenging activity compared with extract-free control formulations (p 0.05). Among the tested extracts, formulations containing Olea europaea and Hypericum perforatum exhibited the highest antioxidant activity. A dose-dependent increase in radical scavenging activity was observed with increasing formulation volume. Fig 11 DPPH radical scavenging activity of artificial saliva formulations containing different plant extracts. Data are presented as percentage inhibition, with extract-free formulations serving as controls. A dose-dependent increase in antioxidant activity was observed.