Developing a Nursing Early-Intervention Bundle to Decrease the Prevalence of Post-Intensive Care Syndrome

Post-intensive care syndrome (PICS) has become an increasingly recognized challenge in critical care as more patients survive prolonged mechanical ventilation and lengthy ICU stays. Although lifesaving interventions support recovery from the primary illness, many patients develop new or worsened physical, cognitive, or psychological impairments after discharge. These complications often limit independence, slow recovery, and create long-term burdens for both patients and families. Research shows that early, consistent nursing interventions, such as delirium prevention, early mobility, mental health support, and family communication, can reduce the risk of PICS. The absence of a unified and standardized approach results in inconsistent practices and missed opportunities for early intervention. This study proposes a structured, nurse-driven early intervention bundle integrated into Epic documentation to promote early assessment, strengthen continuity of care, and reduce PICS incidence among mechanically ventilated ICU patients.