Meta-Analysis: Diabetes Mellitus and the Risk of Endometrial Cancer

Background: Many studies have looked at the relationship between diabetes mellitus and development of endometrial cancer. This study provides an updated systematic review and meta-analysis of the estimated effect of diabetes and the risk of endometrial cancer. Methods: Some studies were found on databases such as PubMed and Iceberg. The remaining studies were extracted from the initial studies found. Binary data was collected and the raw data was imputed into a Fixed Effects Model. Results: A total of 25 studies were included in this meta-analysis, generating statistically significant results (p < 0.001, OR 2.05, 95% Cl 1.92-2.19). Discussion: Diabetes is found to be a significant risk factor to the risk of developing endometrial cancer. Further studies needed to help develop higher standards of care in preventative health.