Comparing the Minimum Inhibitory Concentrations and Minimum Fungicidal Concentrations of Antifungal Drugs in Microsporum canis
Abstract
To assess the minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of itraconazole (ITCZ), terbinafine (TBF), and miconazole (MCZ) in eight isolates of Microsporum canis. The MICs in the eight tested strains were < 0.03 mg/L for TBF, < 0.03 to 0.125 mg/L for ITCZ, and 1 to 4 mg/L for MCZ. The MFCs in the eight strains were 0.5 to 2 mg/L for TBF, 2 to > 32 mg/L for ITCZ, and 16 to > 32 mg/L for MCZ. These results suggested that there were strains with MFC concentrations much higher than the MIC concentrations, indicating fungistatic activity.
Fields of Study & Subjects
Fungal Plant Pathogen Control
Nail Diseases and Treatments
Garlic and Onion Studies
Publication details
- Journal / source
- Medical Mycology Journal
- Publisher
- The Japanese Society for Medical Mycology
- Volume
- 67
- Issue
- 1
- Pages
- 79–81
- Publication date
- 31 January 2026
- Language
- EN