Biofilm and Dermatophytoma

Medical Mycology Journal 2026 Open access

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Authors: Tomotaka Sato, Norihito Fukada, Hisashi Kobayashi, Aya Okaniwa, Miyuki Okada, Kazuto Yamazaki
DOI: 10.3314/mmj.26.006
Cited by: 0
References: 29

Abstract

Dermatophytoma is a type of onychomycosis with distinctive clinical features. Clinically, it typically appears as a linear spike, triangular, or round white- or yellow-colored mass on the nail plate. Dermatophytes are thought to adhere to the nail surface and secrete extracellular polysaccharides (EPS), proteins, DNA, and other components, forming a biofilm matrix. EPS typically encases this microbial aggregation and is synthesized by the microbial constituents of the biofilm. Herein, we review dermatophytoma and the relationship between nail infection and biofilm. We also discuss green nails with dermatophytoma and infection models of biofilm formation.

Fields of Study & Subjects

Nail Diseases and Treatments Antifungal resistance and susceptibility Fungal Infections and Studies

Publication details

Journal / source
Medical Mycology Journal
Volume
67
Issue
1
Pages
71–77
Publication date
31 January 2026
Language
EN