First Experience in Treatment of Papillary Thyroid Cancer with Metastatic Lung Infection in a 12-year-old Patient (Clinical Case)

Purpose: To demonstrate the successful experience of using systemic radioiodine therapy in the treatment of thyroid cancer in children. Material and methods: In the FSBI FSCCRO of FMBA of Russia, as part of the implementation of the State assignment of FMBA of Russia, the development of a modern tool for epidemiological analysis of the results of the use of 131I radionuclide therapy in the treatment of thyroid cancer in the system of FMBA of Russia is carried out. Over 2.5 years of studies, data on the carrying out of radioiodine therapy for thyroid cancer in the nuclear medicine centers of the FMBA institutions of Russia have been studied on more than 1500 patients from different parts of the Russian Federation. The necessary medical documentation and clinical and anamnestic data of patients who underwent radioiodine therapy have been studied, and information has been collected and analyzed epidemiologically, and entered into an electronic database of patients of different age groups. However, in our database clinical cases of children’s treatment are quite rare. Results: Due to the lack of an evidence based on prospective and retrospective studies with a large sample of pediatric patients, a significant portion of the treatment concepts for differentiated thyroid cancer in children are derived from the experience of treating adult patients. However, the more aggressive course of the disease in children, coupled with a good overall prognosis and a long life expectancy, during which adverse effects of radioiodine therapy may occur, requires a personalized approach, as demonstrated in our clinical case. Conclusion: Based on the above, it is evident that it is necessary to develop special recommendations for the treatment and monitoring of pediatric patients with thyroid neoplasms.