Evaluation of the Effectiveness of Ridge Preservation Using β-Tricalcium phosphate, Platelet Rich Fibrin and Recombinant Bone Morphogenetic Proteins (rhBMP-2) Followed by Delayed Implant Placement-A Clinical and Radiographic Study

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Authors: Khushboo Durge, Bhairavi Kale, Pavan Suresh Bajaj, Prasad Dhadse, Manohar Laxmanrao Bhongade, Kiran Kumar Ganji, Mohammed Ghazi Sghaireen, Mohammad Khursheed Alam
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Abstract

Background The successful insertion of dental implants is highly proportional to the condition and quantity of the alveolar bone at the edentulous area. This pilot study aimed at evaluating clinically & radiographically the efficacy of preservation of alveolar ridge by making use of platelet- rich fibrin (PRF) & β – tricalcium phosphate {TCP)+rh- bone morphogenic protein (BMP)-2 followed by delayed implant placement. Materials & Methods Post-extraction sockets were augmented using a combination of autologous PRF and alloplastic bone graft (β-TCP) mixed with growth factor rh-BMP 2. At three months, the clinical and radiographic study was carried out, and implants were placed using two staged protocols. Outcome clinical parameters involving mean modified plaque index (MPI), modified bleeding index (MBI), clinical implant mobility score (CIMS), full mouth plaque index (FMPI), full mouth papillary bleeding index (FMPBI), probing measurements such as probing pocket depth (PPD), gingival recession (GR), and width of keratinized gingiva (WKG) around implants were evaluated. Results A total of 12 sockets in 9 patients were treated using the ridge preservation technique. At three months after extraction & ridge preservation, baseline evaluation revealed minimal buccolingual dimensional changes (7.0 mm ± 1.21 mm). Following implant placement, radiographic evaluation at 3 months showed minimum vertical & horizontal loss in bone (mesial: 0.33 ± 0.33, distal: 0.25 ± 0.33). Use of rhBMP-2+ β -TCP+rh-BMP-2 reduces the dimensional changes owing to 100% survival of the implants. Conclusion Atraumatic extraction employing ridge preservation using PRF & β -TCP+rh-BMP-2 followed by delayed implant placement minimizes dimensional changes and helps in the improved success rate of the implant BJMS, Vol. 25 No. 01 January’26 Page : 334-342

Fields of Study & Subjects

Dental Implant Techniques and Outcomes Periodontal Regeneration and Treatments Bone Tissue Engineering Materials

Publication details

Journal / source
Bangladesh Journal of Medical Science
Volume
25
Issue
1
Pages
334–342
Publication date
26 January 2026