Synthesis of Ethyl 3,5-(Disubstituted Phenyl)-2-Isocyano-5-Oxopentanoate

Dhaka University Journal of Science 2026 Open access

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Authors: Kawsari Akhter, Roksana Akter, S Mosaddeq Ahmed, M. Ershad Halim
DOI: 10.3329/dujs.v74i1.83479
Cited by: 0

Abstract

The reactions between substituted chalcones 1a-d with ethyl cyanoacetate 2 were carried out in 1:1 molar ratio in the presence of sodium ethoxide as catalyst under refluxing condition to synthesize few chalcone derivatives, ethyl 3,5- (disubstituted phenyl)-2-isocyano-5-oxopentanoate, 3a-d. The structure of the compounds was determined by their chemical properties, UV, FT-IR, 1H-NMR, 13C-NMR, mass spectral data and elemental analyses. Dhaka Univ. J. Sci. 74(1): 122-126, 2026 (January)

Fields of Study & Subjects

Synthesis and biological activity Synthesis of Organic Compounds Synthesis of heterocyclic compounds

Publication details

Journal / source
Dhaka University Journal of Science
Volume
74
Issue
1
Pages
122–126
Publication date
28 January 2026