Association Between Perioperative Hypoalbuminemia And Anastomotic Leakage In Esophageal Carcinoma Patients Undergoing Esophageal Resection

Background: Anastomotic Leakage (AL) is a serious complication after esophagectomy, increasing morbidity, hospital stay, and mortality. Hypoalbuminemia may predict AL, but its early postoperative role is unclear. To assess the association between early postoperative serum albumin and AL in esophageal cancer patients underwent esophagectomy. Materials and methods: In this prospective study, 84 patients with confirmed esophageal carcinoma underwent curative esophagectomy. Serum albumin was measured on postoperative day one. Patients were monitored for AL and other complications. Chi-square, t-test, and multivariate logistic regression were used to identify predictors of AL. Results: Mean age was 55.8 ± 9.1 years, 78.6% were male. AL occurred in 20.2% (17/84). Hypoalbuminemia (