Large Language Models in Spine Surgery : A Narrative Review of Performance Paradox and Clinical Integration Challenges

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Authors: Sung Bum Kim, Il‐Tae Jang, YooKyung Lee, Yoon Gyo Jung, SangSoo Choi, Jun-Yong Cha
Cited by: 1
References: 42

Abstract

To provide a narrative synthesis of the performance paradox in large language model (LLM) applications for spine surgery, examining the disparity between technical metrics and clinical utility. A narrative review was conducted examining literature from January 2023 to February 2026 across PubMed, EMBASE, and Google Scholar. Studies evaluating LLM applications in spine surgery were included, with emphasis on newer models (GPT-4o, GPT-5, Claude, Gemini variants, DeepSeek). Studies were thematically analyzed across clinical documentation, patient communication, and surgical decision-making domains. Analysis of 42 studies revealed a consistent pattern across applications. LLMs performed strongly in structured documentation tasks, including current procedural terminology coding (area under the receiver operating characteristic curve, 0.87) and surgical classification (91% accuracy), and improved readability in patientfacing materials. Patient communication achieved high satisfaction rates but demonstrated limited emotional intelligence. In contrast, decision-making performance was more variable: in small vignette-based comparisons, LLMs showed lower raw accuracy than attending spine surgeons in complex scenarios, and guideline concordance ranged from 33% to 88% across models. Emerging evidence with nextgeneration models suggests incremental gains, but procedure-level agreement remains limited (κ=0.415 and 0.587 in minimally invasive spine surgery triage). Image-based tasks, such as Cobb angle measurement, remain particularly challenging, with all tested models failing to meet the ≤10° clinical threshold. LLMs show near-term utility in standardized text-based tasks, but current evidence does not support autonomous use in complex clinical decision-making or image-based spinal assessment. Staged implementation with mandatory human oversight remains necessary.

Fields of Study & Subjects

Medical Imaging and Analysis Artificial Intelligence in Healthcare and Education Machine Learning in Healthcare

Publication details

Journal / source
Journal of Korean Neurosurgical Society
Publisher
Korean Neurosurgical Society
Volume
69
Issue
5
Pages
674–682
Publication date
31 March 2026
Language
EN