Outcome of mirabegron therapy on urodynamically proven overactive bladder versus symptoms based overactive bladder in adult

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Authors: Shrabanti Dhar, ATM Aman Ullah, Muhammad Serajul Islam, Abdullah Al Mamun, Dr. Md. Mazedur Rahman, Md. Omar Faruk, Md. Abu Nahid, Muhammed Zafar Iqbal
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Abstract

Detrusor overactivity (DO) is the underlying pathology of overactive bladder (OAB) confirmed by urodynamic study (UDS), although symptomatic diagnosis alone may not always correlate with urodynamic findings. Prospective quasi-experimental study was conducted to compare the outcomes of mirabegron therapy among 83 patients divided into 2 groups- Group A, Group A (urodynamically proven) and Group B (symptoms based OAB). After 6 months of treatment, 57.1% of patients in Group A showed mild symptoms and 42.9% had moderate symptoms, while in Group B, 12.2% had mild and 87.8% had moderate symptoms. The reduction in overactive bladder symptom score (OABSS) and urgency episodes per 24 hours was significantly greater in Group A than in Group B (p

Fields of Study & Subjects

Urinary Bladder and Prostate Research Pelvic floor disorders treatments Urinary Tract Infections Management

Publication details

Journal / source
International Journal of Urology Research
Volume
8
Issue
1
Pages
21–26
Publication date
1 January 2026
Language
EN