Precision-based motor learning enhances neuroplasticity and hand function in post-stroke individuals: A randomized controlled trial

Background: Precision-Based Motor Learning (PBML) focuses on task accuracy, sensory feedback, and controlled motor repetition, aimed at promoting neuroplasticity after stroke. Evidence suggests that targeted motor learning strategies may enhance cortical reorganization and functional recovery. Objective: To evaluate the effects of PBML on neuroplastic adaptations and upper-limb motor recovery in individuals with post-stroke impairment. Methods: Thirty-six participants with chronic stroke were randomly allocated to either PBML training (N=18) or conventional motor practice (N=18). Both groups trained 5 days/week for 8 weeks. Outcome measures included Fugl-Meyer Upper Extremity (FMA-UE), grip strength, Box and Block Test (BBT), and somatosensory discrimination tasks. Pre-post scores were analyzed using paired and independent t-tests (p