Contrast-enhanced MRI (CE MRI) and diffusion weighted imaging MRI (DWI MRI) in differentiating benign and malignant ovarian lesions: Can it replace histopathology? Study from a Himalayan valley of India

Background: Ovarian masses present significant diagnostic challenges, particularly in distinguishing benign and malignant lesions. Accurate differentiation is critical for appropriate treatment planning, as ovarian cancer remains one of the major lethal malignancies among females. Late diagnoses contribute to poor outcomes, highlighting the need for improved detection methods. Objective: To evaluate the effectiveness of Contrast Enhanced Magnetic Resonance Imaging (CE-MRI) and Diffusion-Weighted Imaging (DWI) in distinguishing benign from malignant ovarian lesions, thereby enhancing diagnostic accuracy. Methods: This prospective observational study included 34 women presenting with ovarian masses, conducted over 22 months in the Department of Obstetrics and Gynecology, Surgical Oncology and Radiodiagnosis at SKIMS, Srinagar. All participants underwent CE MRI and DWI MRI. Imaging findings were correlated with histopathological/biopsy results. The analysis of data was done with the help of SPSS software (version 25) with p