Simultaneous Buccal Mucosa Composite Resection with Total Laryngectomy for Double Synchronous Primary Squamous Cell Carcinoma: A Case Report and Literature Review

The emergence of synchronous primary malignancies within the context of head and neck squamous cell carcinoma (HNSCC) constitutes a rare yet clinically pertinent dilemma, manifesting in approximately 5.3% of HNSCC patients. Treatment in such clinical conditions requires a multidisciplinary approach. This article describes a unique case involving double synchronous primary squamous cell carcinomas of soft palate area and larynx, post chemoradiotherapy. As a salvage treatment patient underwent composite resection along with total laryngectomy in same surgery. At the conclusion of five years, he remained free from disease and experienced an adequate quality of life.