Relationship between Allopregnanolone levels and duration of implant use for depression

Hellenic Journal of Obstetrics and Gynecology 2026

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Authors: Jeanette M. Choukrosimon, Sriwijaya, Irnawaty Bahar, Samrichard Rambulangi, Fatmawati Madya, Nurbani Bangsawan
DOI: 10.33574/hjog.0613
Cited by: 0

Abstract

Introduction: The use of hormonal contraceptives, such as progestin implants, is suspected to affect allopregnanolone levels and involved in mood regulation, potentially increasing depression risk. This study aimed to analyze the correlation between allopregnanolone levels and the duration of implant use on depression among implant acceptors compared to intrauterine device (IUD) users. Material and methods: A cross-sectional study involved 90 women aged 20–35 years, divided into three groups: implant users

Fields of Study & Subjects

Reproductive Health and Contraception Estrogen and related hormone effects Maternal Mental Health During Pregnancy and Postpartum

Publication details

Journal / source
Hellenic Journal of Obstetrics and Gynecology
Volume
25
Issue
1
Pages
34–42
Publication date
15 January 2026