Assessment of Toxicity in the Extract of the Herb Betonica

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Authors: Evgeniy Evgen'yevich Kurdyukov, Aleksandr Vladimirovich Mitishev, Nadezhda Valeryevna Finaenova, Е. Saraikin, D. Koflyuk
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Abstract

The acute, subacute and chronic toxicity of an extract from the herb Betonica officinalis in laboratory rats was studied. Acute toxicity: LD50 > 5000 mg/kg (orally). Subacute (28 days, upto 2000 mg/kg) and chronic (180 days, up to 900 mg/kg) toxicity: no significant changes in general condition, hematological, biochemical parameters and pathomorphological changes were detected. Conclusion: Medicinal letter letter extract is non-toxic and promising for further pharmacological studies.

Fields of Study & Subjects

Phytochemistry Medicinal Plant Applications Medicinal Plant Research Plant Toxicity and Pharmacological Properties

Publication details

Journal / source
Bulletin of Science and Practice
Volume
12
Issue
1
Pages
150–154
Publication date
13 January 2026
Language
RU