Impact of healthcare system collapse on hospital-acquired infection dynamics: a mathematical approach

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Authors: Maria M. Shaale, Luke Oluwaseye Joel, Farai Nyabadza
Cited by: 1
References: 25

Abstract

The collapse of healthcare systems poses a serious threat to hospital environments, increasing the spread of nosocomial infections. Limited resources, overcrowding, and weakened infection control measures allow harmful pathogens to persist on surfaces, medical equipment, and in the air. Consequently, patients and healthcare workers face a higher risk of infection, leading to increased morbidity. In this study, we develop a mathematical model to examine how a failing healthcare system influences the spread of nosocomial infections in hospitals. The model properties, such as the positivity and boundedness of solutions, are established. The disease-free equilibrium is determined and its stability is analyzed using the basic reproductive number R 0 . Model simulations are performed to determine the influence of some important parameters on the reproduction number of the model. The findings show that a collapsing healthcare system significantly affects the control of nosocomial infections in hospitals, as inadequate infection control measures lead to a more contaminated environment. Therefore, strengthening healthcare systems is essential to reducing nosocomial infections and ensuring safer hospital environments. These results have huge implications for the management of nosocomial infections in hospitals. 2000 MSC: 34C11, 34C60, 92B05

Fields of Study & Subjects

Infection Control in Healthcare Infection Control and Ventilation Nosocomial Infections in ICU

Publication details

Journal / source
Frontiers in Applied Mathematics and Statistics
Publisher
Frontiers Media SA
Volume
11
Publication date
23 January 2026