Accusafe guidewire for atrial septal puncture: dual-imaging safety and efficacy: a case report

Frontiers in Cardiovascular Medicine 2026 Open access

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Authors: Qian Nie, Haseeb Sattar, Ailing Huang, Hongcai Zhang, Jue Zhao, Delai Zhang, Xie Wen
DOI: 10.3389/fcvm.2026.1652997
Cited by: 0
References: 5

Abstract

A 74-year-old female with nonvalvular atrial fibrillation and heart failure, on rivaroxaban 20 mg/day, presented for left atrial appendage (LAA) closure due to recurrent hematomas despite anticoagulation therapy. This case report describes an innovative atrial septal puncture (ASP) technique utilizing the Accusafe guidewire (Synaptic Medical, Beijing, China) under combined fluoroscopic and intracardiac echocardiography (ICE) guidance. The procedure was successful, demonstrating that this method may enhance procedural safety and precision, particularly in complex cases such as LAA closure, atrial fibrillation ablation, and MitraClip procedures.

Fields of Study & Subjects

Atrial Fibrillation Management and Outcomes Cardiac Arrhythmias and Treatments Cardiovascular and Diving-Related Complications

Publication details

Journal / source
Frontiers in Cardiovascular Medicine
Volume
13
Pages
1652997–1652997
Publication date
9 February 2026
Language
EN