A modifiable imaging biomarker: epicardial adipose tissue density in ischemia with non-obstructive coronary arteries

Frontiers in Cardiovascular Medicine 2026 Open access

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Authors: Fan Sun, Yu Tian, Wenji Yu, X Song, Feifei Zhang, Yi-Xiang Wang, Xiaoliang Shao, Bao Liu, Xiaoyu Yang, Peng Wan, Yongjun Chen, Sijin Li
+1 more Yuetao Wang
DOI: 10.3389/fcvm.2026.1686602
Cited by: 1
References: 49

Abstract

Background The impact of epicardial adipose tissue (EAT) on the risk of non-obstructive coronary artery disease (CAD) remains unclear. This study aims to investigate the association between EAT and ischemia with non-obstructive coronary arteries (INOCA). Methods This study enrolled 281 patients with angina or other symptoms suggestive of myocardial ischemia who underwent single-photon emission computed tomography myocardial perfusion imaging (SPECT-MPI). All patients had confirmed non-obstructive coronary artery disease (stenosis

Fields of Study & Subjects

Cardiovascular Disease and Adiposity Adipokines Inflammation and Metabolic Diseases Cardiovascular Function and Risk Factors

Publication details

Journal / source
Frontiers in Cardiovascular Medicine
Publisher
Frontiers Media SA
Volume
13
Pages
1686602–1686602
Publication date
30 January 2026
Language
EN