Latent profile analysis of health status and influencing factors among patients with coronary heart disease based on patient-reported outcomes

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Authors: Hong Jiang, Xiaochun He, Yuan Huang, Jingjing Tan, Xixi Li, Zhan Li
Cited by: 1
References: 32

Abstract

Background Coronary heart disease is a leading cause of mortality and disability worldwide, posing significant challenges to public health and necessitating effective strategies for improving patient outcomes and quality of life.This study aims to analyze the health status of Coronary heart disease patients using a patient-reported outcomes scale, exploring differences across five dimensions: physical health, mental health, social health, spiritual health, and specific symptoms. The goal is to provide a foundation for personalized medical interventions and health management. Methods This is a Cross-sectional study, 240 patients were selected for latent profile analysis to categorize their health statuses. Key influencing factors were identified through univariate analysis and multivariate logistic regression analysis. Results The health status of patients was categorized into three groups, stable and healthy model ( n = 146), social psychological fluctuation model ( n = 78), and symptom prominent instability model ( n = 16). Significant differences were observed among these concerning glycated hemoglobin, high-density lipoprotein, low-density lipoprotein, age, monthly income, education level, and comorbid chronic obstructive pulmonary disease. The health status of social psychological fluctuation model and symptom prominent instability model was independently influenced by glycated hemoglobin, age, education level, and COPD ( P < 0.05). Conclusion The health status of CHD patients can be classified into distinct categories influenced by multiple factors and comorbidities. As a crucial assessment tool, PRO facilitates the categorization of patient health statuses and provides a reference for precision medicine and personalized interventions. Future efforts should focus on developing targeted interventions tailored to the specific characteristics.

Fields of Study & Subjects

Cardiac Health and Mental Health Cardiovascular Health and Risk Factors Health disparities and outcomes

Publication details

Journal / source
Frontiers in Cardiovascular Medicine
Publisher
Frontiers Media SA
Volume
13
Pages
1739066–1739066
Publication date
23 January 2026
Language
EN