Metabolic syndrome and high-sensitivity C-reactive protein co-modify the risk of coronary artery calcification

Frontiers in Cardiovascular Medicine 2026 Open access

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Authors: Li‐Yu Chen, Yijia Chen, Vy-Khanh Nguyen, Chung-Kuan Wu
DOI: 10.3389/fcvm.2026.1759522
Cited by: 1
References: 51

Abstract

Background: Coronary artery calcification (CAC) is a marker of subclinical atherosclerosis and is strongly associated with coronary artery disease (CAD). Metabolic syndrome (MetS) and high-sensitivity C-reactive protein (hs-CRP), an inflammatory marker, have each been linked to CAC, but their combined influence remains unclear. Methods: This cross-sectional study included 1948 adults undergoing health checkups and coronary calcium scoring via computed tomography. Participants were grouped by MetS status and hs-CRP levels (

Fields of Study & Subjects

Adipokines Inflammation and Metabolic Diseases Cardiac Imaging and Diagnostics Cardiovascular Disease and Adiposity

Publication details

Journal / source
Frontiers in Cardiovascular Medicine
Publisher
Frontiers Media SA
Volume
13
Pages
1759522–1759522
Publication date
30 March 2026
Language
EN