Association between elevated C-reactive protein-triglyceride-glucose index and in-hospital major adverse cardiovascular events in acute coronary syndrome patients after percutaneous coronary intervention: a single-center prospective observational study

Objective: Inflammation and metabolic disorders play important roles in the pathogenesis of acute coronary syndrome(ACS). The C-reactive protein-triglyceride-glucose index(CTI) is a novel combined inflammatory-metabolic indicator. This study aimed to evaluate the association between CTI and in-hospital major adverse cardiovascular events(MACE) in ACS patients after percutaneous coronary intervention(PCI). Methods: This prospective observational study consecutively enrolled 300 patients who underwent PCI for ACS at our hospital from January 2023 to October 2025. C-reactive protein(CRP),triglyceride(TG), and fasting plasma glucose (FPG) were measured upon admission, and CTI values were calculated. Patients were divided into Q1-Q4 groups according to CTI quartiles. The primary endpoint was in-hospital MACE, defined as a composite of cardiac death, acute stent thrombosis, recurrent myocardial infarction, acute heart failure, and cardiogenic shock. Multivariate logistic regression analysis was used to assess the association between CTI and in-hospital MACE. Results: 44. 0%, P