Glycemic control, including Time in Tight Range (TITR) evaluation, in children with type 1 diabetes treated with the MiniMed 780G system: a 3-year prospective, observational, two-center study

Background: The MiniMed 780G was the first commercially available automated insulin delivery (AID) system in Poland. The aim of this study was to analyze glycemic management in children with type 1 diabetes (T1D) after three years of using the system. Materials and methods: The data included anthropometric measurements, information from insulin pumps, and continuous glucose monitoring (CGM) from fifty children with T1D (mean age: 9.9 ± 2.4 years; T1D duration at baseline: 3.9 ± 2.56 years) using the MiniMed 780G. The data were collected at AID initiation, 12 and 36 months after starting its use. Results: Coefficient of variation (CV) and body mass index (BMI) z-scores at baseline and after 3 years were comparable (p > 0.05). TITR firstly increased after the AID system implementation with the peak value after 6 months (60.82% ± 9.34), then the values decreased to 56.50%± 10.78% after 3 years (p