Central precocious puberty in Türkiye, 2018–2024: national incidence, prevalence, and changes across the COVID-19 period

Frontiers in Endocrinology 2026 Open access

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Authors: Emre Özer, Seçil Çakır Gündoğan, Abdurrahman Bitkay, Neslihan Öztürk, Naim Ata, Şuayip Birinci, Aylin Kılınç Uğurlu, Onur Akın
DOI: 10.3389/fendo.2026.1773426
Cited by: 2
References: 26

Abstract

Background: Rates of central precocious puberty (CPP) are increasing worldwide; however, contemporary population-based studies remain limited in many settings, including Türkiye, and temporal patterns across the COVID-19 period are incompletely characterised. To address these gaps we aimed to quantify national incidence and prevalence of treated CPP from 2018 to 2024 and to describe temporal patterns across the COVID-19 period and geographic variation. Methods: We conducted a retrospective, population-based registry study using Türkiye's national electronic health record system (e-Nabız). For incidence analyses, we included girls aged

Fields of Study & Subjects

Hypothalamic control of reproductive hormones Ectopic Pregnancy Diagnosis and Management Ovarian function and disorders

Publication details

Journal / source
Frontiers in Endocrinology
Publisher
Frontiers Media SA
Volume
17
Pages
1773426–1773426
Publication date
10 March 2026
Language
EN