A randomized controlled trial examining the impact of diversified nursing interventions on the circadian rhythm of sedated critically ill patients

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Authors: Mengfei Zhang, Aili Shi, Chen Xia, Liping Du, Shuangqin Zheng, Yong Nan, Zhen Cheng
Cited by: 0
References: 29

Abstract

Background: Circadian rhythms are cyclical processes within an organism that develop over time for the organism to better adapt to its environment. Disruption of the circadian rhythm by various factors can have both acute and chronic adverse effects on the health of the organism. Sedated patients in the intensive care unit often have severe circadian rhythm disturbances, in which care-related exogenous factors play an important role. Methods: In this study, a randomized controlled trial design was adopted. Starting from the exogenous factors of nursing, the research objects that met the inclusion criteria were numbered. According to the inclusion order, they were odd numbered into the control group (receiving routine nursing care) and even numbered into the experimental group (receiving diversified nursing intervention). The two groups of research objects were divided into different sedation degree groups according to Richmond Agitation Sedation Scale (RASS) scores, which were divided into RASS 0-2 group, RASS -3-4 group and RASS -5 group, a total of six groups. The influence of diversified nursing intervention measures on patients' circadian rhythm was evaluated by measuring the melatonin levels of the two groups. Results: < 0.05), indicating that diversified nursing interventions had a beneficial role in treating circadian rhythm disorders among sedated ICU patients. Conclusion: The circadian rhythm is crucial for critically ill patients and can be improved through diversified nursing interventions. This study provides relevant data for the future treatment of patients presenting with circadian rhythm disorders in the intensive care unit.

Fields of Study & Subjects

Circadian rhythm and melatonin Intensive Care Unit Cognitive Disorders Family and Patient Care in Intensive Care Units

Publication details

Journal / source
Frontiers in Medicine
Volume
12
Pages
1655844–1655844
Publication date
12 January 2026
Language
EN