Association of lifestyle, physiological factors, and body composition with the facial skin microbiota in acne vulgaris

Introduction: The skin microbiota plays a crucial role in maintaining skin health and overall well-being. The composition of this microbial community is influenced by various host factors, including lifestyle habits, physiological parameters, and body composition. Methods: 1,053 participants were included in this study. The composition of the skin microbiota was determined by analysing facial skin microbiome collection, obtained after the consent of participants. Also, physical characteristics of each participant were evaluated using answers from questionnaire. Potential microorganisms that contribute to acne vulgaris development were investigated. Statistical analysis was then performed based on the characteristics of the patient and normal groups, and the differences in the bacterial ratio grade assigned to each individual. Results: were significantly correlated with acne vulgaris. Several characteristics of the participants were closely correlated with the composition of the skin microbiota. There was significant differences among the participants' characteristics. Discussion: By analyzing the body composition and daily life of the study subjects, we identify associations of acne vulgaris and suggest specific lifestyle modifications that may be beneficial for acne sufferers.