Combination of sodium-glucose cotransporter type 2 inhibitors and urate-lowering therapy in people with gout from a specialist clinic: a retrospective, single-center observational study

Frontiers in Medicine 2026 Open access

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Authors: Jose Doménech-Serrano, I. Garcia-Loiseau, Cristina Rodríguez-Alvear, Pablo Riesgo-Sanchis, Óscar Moreno-Pérez, Mariano Andrés
DOI: 10.3389/fmed.2025.1726111
Cited by: 2
References: 39

Abstract

To evaluate the effectiveness of sodium-glucose cotransporter type 2 (SGLT2) inhibitors combined with traditional urate-lowering therapy (ULT) in people with gout, we conducted a retrospective, single-center observational study in a crystal arthritis clinic. Primary outcomes were reduction in serum urate (SU) levels and achievement of SU targets (

Fields of Study & Subjects

Gout Hyperuricemia Uric Acid Thyroid Disorders and Treatments Kidney Stones and Urolithiasis Treatments

Publication details

Journal / source
Frontiers in Medicine
Publisher
Frontiers Media SA
Volume
12
Pages
1726111–1726111
Publication date
12 January 2026
Language
EN