Update of the sequential organ failure assessment score: current status and challenges?

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Authors: Jiafei Yu, Kangwei Sun, Yiping Zhou, Yushi Fan, Xinyun Zhang, Heyu Chen, Lanxin Cao, Kai Zhang, Gensheng Zhang
Cited by: 4
References: 49

Abstract

The sequential organ failure assessment (SOFA) score has been widely used for approximately 30 years for the clinical assessment and monitoring of organ dysfunction in patients. However, advancements in medical science and clinical practice have identified several limitations of the SOFA score, underscoring the need for its revision. This paper synthesizes and summarizes the recent advances and provides a comprehensive understanding of the deficiencies of the SOFA score, which requires certain refinements. Furthermore, this work presents a scientific basis and direction for further modifications to enhance the clinical utility of the score.

Fields of Study & Subjects

Acute Kidney Injury Research Sepsis Diagnosis and Treatment Heart Failure Treatment and Management

Publication details

Journal / source
Frontiers in Medicine
Publisher
Frontiers Media SA
Volume
12
Pages
1733090–1733090
Publication date
13 January 2026
Language
EN