Diabetic cardiomyopathy from a gut microbiota perspective: research progress and prospects
Abstract
Recent evidence indicates that gut microbiota dysbiosis impairs intestinal barrier function, induces endotoxemia, and consequently triggers systemic inflammatory cascades. Advances in gut microbiota research have further elucidated its critical role in the pathogenesis of diabetes and its complications. This review examines the relationship between diabetic cardiomyopathy and gut microbiota, delineating microbial metabolite-mediated and immunomodulatory influences on myocardial function, while proposing novel therapeutic strategies.
Fields of Study & Subjects
Gut microbiota and health
Oral microbiology and periodontitis research
Cardiac Fibrosis and Remodeling
Publication details
- Journal / source
- Frontiers in Medicine
- Volume
- 12
- Pages
- 1737326–1737326
- Publication date
- 12 January 2026
- Language
- EN