Sarcopenia in type 2 diabetes mellitus: an imaging review

Frontiers in Medicine 2026 Open access

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Authors: Lei He, Guanghua Luo, Hongtao Jiang, Zhang Li, Yusheng Li, Wenbin Gu, Qiqun Zeng, Jingjun Zhu, Jincai Liu, Hao Lei, Heng Zhao
DOI: 10.3389/fmed.2026.1637499
Cited by: 3
References: 187

Abstract

Sarcopenia is characterized by an age-related decline in muscle mass, strength, or endurance. It is increasingly prevalent in patients with type 2 diabetes mellitus (T2DM) and is now regarded as a key complication of the disease. Additionally, it has a significant impact on patients' prognosis. Imaging methods are crucial tools for assessing muscle mass and microchanges. Moreover, they can facilitate the early diagnosis of sarcopenia. Thus, this article reviews the pathological basis and clinical manifestations of sarcopenia in T2DM, the advantages and disadvantages of imaging assessment methods, their specific applications, imaging manifestations, and research progress.

Fields of Study & Subjects

Nutrition and Health in Aging Muscle Physiology and Disorders Body Composition Measurement Techniques

Publication details

Journal / source
Frontiers in Medicine
Publisher
Frontiers Media SA
Volume
13
Pages
1637499–1637499
Publication date
21 January 2026
Language
EN