Case Report: Bilateral panuveitis with serous ciliary body and choroidal detachment associated with ulcerative colitis

Purpose: To report a rare case of ulcerative colitis (UC)-associated bilateral panuveitis presenting with serous ciliary body detachment and choroidal detachment. Case description: A 51-year-old Asian woman with a history of UC presented with a 10-day history of bilateral blurred vision, ocular pain, redness, and photophobia. At presentation, her best-corrected visual acuity (BCVA) was 20/60 in the right eye and 20/100 in the left eye, with normal intraocular pressure. Slit-lamp examination showed signs of anterior uveitis. Fundus examination revealed bilateral optic disk edema and peripheral choroidal detachment in the left eye. Indocyanine green angiography showed multiple patchy hypofluorescent lesions in the posterior pole. Optical coherence tomography confirmed choroidal thickening and disk swelling, and ultrasound biomicroscopy demonstrated bilateral serous ciliary body detachment. After excluding other systemic and ocular etiologies, a diagnosis of bilateral UC-associated panuveitis was made. The patient received topical steroids, retrobulbar injection of triamcinolone acetonide in the left eye and oral prednisone initiated at 60 mg/day and tapered gradually. Her BCVA improved to 20/20 in the right eye and 20/30 in the left eye after 9 months follow-up. Conclusion: UC-associated uveitis can manifest as bilateral panuveitis with ciliary body and choroidal detachment. Prompt diagnosis and immediate initiation of systemic corticosteroid therapy are critical for achieving optimal anatomical restoration and visual prognosis.