Case Report: A case of toxic epidermal necrolysis induced by serplulimab: integrated Chinese and Western nursing care
Abstract
This study summarizes the integrated Chinese and Western medical nursing experience for a lung cancer patient admitted to our hospital in 2025 who developed toxic epidermal necrolysis (TEN) following treatment with serplulimab. Medical staff provided personalized care addressing the patient's skin and mucosal lesions, pain, and psychological wellbeing, aiming to establish evidence for the future treatment and management of such symptoms. Following multidisciplinary consultation and 39 days of meticulous treatment and nursing care, the patient's widespread skin erosion largely healed, with no new rashes observed, ultimately leading to discharge in an improved condition.
Fields of Study & Subjects
Drug-Induced Adverse Reactions
Pharmacovigilance and Adverse Drug Reactions
Cancer Immunotherapy and Biomarkers
Publication details
- Journal / source
- Frontiers in Medicine
- Publisher
- Frontiers Media SA
- Volume
- 13
- Pages
- 1759311–1759311
- Publication date
- 16 February 2026
- Language
- EN