Upadacitinib is effective in treating psoriasis combined with lichen planus: a case report
Abstract
Psoriasis frequently coexists with other immune-mediated conditions such as arthritis, alopecia areata, vitiligo, and hidradenitis suppurativa, many of which remain challenging to manage. To date, there have been rarely reported cases of treating psoriasis combined with lichen planus. We report a case of coexisting psoriasis and lichen planus in a female patient. Despite initial efficacy with acitretin and topical mometasone, the patient self-discontinued treatment over safety concerns, prompting a relapse. Upadacitinib was subsequently initiated and yielded marked improvement within 3 months. By discussing the disease interplay and treatment rationale, this report seeks to inform clinical decision-making.
Fields of Study & Subjects
Psoriasis: Treatment and Pathogenesis
Hidradenitis Suppurativa and Treatments
Oral Health Pathology and Treatment
Publication details
- Journal / source
- Frontiers in Medicine
- Publisher
- Frontiers Media SA
- Volume
- 13
- Pages
- 1771710–1771710
- Publication date
- 20 April 2026
- Language
- EN