A case of solitary bone plasmacytoma to multiple myeloma: a case report

Frontiers in Medicine 2026 Open access

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Authors: Zhimin Fang, Zhong Tian, Jiyang Tang, Bo Lei, Zhongcong He, Cheng Zhu, Huangyu Luo, Ni Fu, Yuguang Shen
DOI: 10.3389/fmed.2026.1774242
Cited by: 1
References: 22

Abstract

Solitary bone plasmacytoma of the rib is uncommon but recognized. We report a case presenting with recurrent, predominantly nocturnal chest wall pain. Imaging revealed an expansile lesion on the left ninth rib and initially suggested fibrous/osteofibrous dysplasia. The patient underwent resection of the involved rib segment. Histopathology and immunohistochemistry confirmed solitary bone plasmacytoma. The patient declined the recommended adjuvant radiotherapy. Twenty-one months later, the disease progressed to multiple myeloma.

Fields of Study & Subjects

Multiple Myeloma Research and Treatments Management of metastatic bone disease Myeloproliferative Neoplasms: Diagnosis and Treatment

Publication details

Journal / source
Frontiers in Medicine
Publisher
Frontiers Media SA
Volume
13
Pages
1774242–1774242
Publication date
25 February 2026
Language
EN