Summary of best evidence for targeted body temperature management in patients with severe neurological illness

Background: To retrieve, synthesise, and evaluate the best practice evidence for targeted temperature management in neurocritical care patients. Methods: A comprehensive search was conducted following the "6S" evidence evaluation framework, utilizing databases such as BMJ Best Practice, UpToDate, JBI Database of Evidence-Based Health Care (Australia), National Guideline Clearinghouse, Cochrane Library, China Biology Medicine disc, Wanfang Data, and China National Knowledge Internet. The search focused on high-quality resources related to targeted temperature management in neurocritical care, including clinical practice decisions, professional guidelines, evidence summaries, and expert consensuses. Two independent researchers conducted the quality assessment and evidence extraction. Results: Twenty documents were included, comprising one clinical decision-making article, seven guidelines, six expert consensus statements, four systematic reviews, and two evidence summaries. These documents yielded 27 best-practice pieces of evidence for targeted temperature management in neurocritical care patients, spanning six aspects: preparation, initiation, maintenance, complication management, rewarming, and prognosis management. Conclusion: The best evidence for targeted temperature management in neurocritical care patients, constructed through an evidence-based approach, provides an optimal basis for decision-making by healthcare professionals.