Case Report: Spontaneous complete uterine rupture in the second and third trimester of pregnancy
Abstract
Objective: To summarize the clinical features, risk factors, and maternal and fetal outcomes of spontaneous complete uterine rupture during the second and third trimester of pregnancy, and to explore key aspects of early identification and management, especially in cases without prior cesarean section. This study aims to provide evidence-based insights for early warning and emergency intervention in clinical practice. Methods: This is a retrospective case series analysis of seven cases of spontaneous complete uterine rupture occurring in the second and third trimester of pregnancy. We analyzed patient demographics, obstetric history, gestational age at rupture, clinical presentation, management strategies, and outcomes. Descriptive statistical methods were employed, with continuous variables expressed as medians (range) and categorical variables as frequencies (percentages). Results: The median age of the seven women was 30 years old, with a median gestational age at rupture of 27 weeks. Among them, 57.1% (4/7) experienced rupture in the second trimester (
Fields of Study & Subjects
Maternal and Perinatal Health Interventions
Pregnancy-related medical research
Preterm Birth and Chorioamnionitis
Publication details
- Journal / source
- Frontiers in Medicine
- Publisher
- Frontiers Media SA
- Volume
- 13
- Pages
- 1802146–1802146
- Publication date
- 15 April 2026
- Language
- EN