Emerging therapeutic targets in non-infectious uveitis and scleritis

Frontiers in Medicine 2026 Open access

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Authors: Usanee Tungsattayathitthan, Debra A. Goldstein, Timothy M. Janetos
DOI: 10.3389/fmed.2026.1846374
Cited by: 1
References: 256

Abstract

Non-infectious uveitis and scleritis are significant causes of visual impairment, and currently available targeted and effective therapeutic options remain limited. Multiple immunologic pathways are currently under investigation and targeted therapeutics have the potential to change the treatment landscape and improve visual outcomes. This review synthesizes potential upcoming local and systemic treatments for non-infectious uveitis and scleritis with a focus on therapeutics with human data, noting those with the most promising evidence, and areas of gaps in research.

Fields of Study & Subjects

Ocular Diseases and Behçet’s Syndrome Leptospirosis research and findings Otitis Media and Relapsing Polychondritis

Publication details

Journal / source
Frontiers in Medicine
Publisher
Frontiers Media SA
Volume
13
Pages
1846374–1846374
Publication date
15 May 2026
Language
EN