Traditional Chinese medicine in influenza treatment: a bibliometric analysis integrating multiple databases

Read full text
Authors: Fangkai He, Jing Xu, Tianlun Yu, Xingyu Zhu, Xing Wang, Jie Yang, Yifei Xia, Fengmei Wu, Shicheng Su
Cited by: 2
References: 84

Abstract

Background: Influenza, a highly contagious respiratory disease, is especially severe for the elderly, children, and immunocompromised individuals. Traditional Chinese medicine (TCM), with its antiviral, immune-modulating, and symptom-relieving properties, has gained attention as a potential treatment. This study uses bibliometric analysis to assess the research trends, hotspots, and progress of TCM in treating influenza. Methods: Literature from the Web of Science Core Collection (WOSCC), Scopus, and PubMed was analyzed using CiteSpace, VOSviewer, and Bibliometrix to explore author collaboration, research trends, clinical trials, and key advancements in TCM for influenza. Result: Research on TCM for influenza has steadily increased since 2000, with a marked surge post-2019 following the COVID-19 pandemic. China leads the field, contributing nearly two-thirds of the publications. Research focuses on TCM interventions, antiviral mechanisms, and immune modulation, with emerging hotspots in network pharmacology and molecular mechanisms. Conclusion: The study shows a steady annual growth rate of 16.94%, reflecting global interest in TCM for respiratory viral infections. Despite China's leadership, international collaboration remains limited (10.23%). Research has shifted from empirical formulations to modern scientific methods, but further large-scale trials are needed to confirm TCM's efficacy.

Fields of Study & Subjects

Influenza Virus Research Studies Andrographolide Research and Applications Metabolomics and Mass Spectrometry Studies

Publication details

Journal / source
Frontiers in Microbiology
Publisher
Frontiers Media SA
Volume
17
Pages
1761339–1761339
Publication date
12 March 2026
Language
EN