Editorial: Transcriptional and post-transcriptional regulatory networks in cellular homeostasis and stress response

The exposure to certain stimuli induces a dynamic regulation of transcription, which can modulate 39 cellular responses to stress. Among these stress factors, High-Power Microwaves (HPM) are 40 becoming increasingly relevant as their applications continue to expand. This raises important 41 questions about potential biological effects and safety. In this regard, Gao et al. observed that 42 exposure of corneal epithelial cells to HPM at 4,3 GHz induces a range of significant cellular changes: regulators, with SGs modulating cellular adaptation. Despite early-stage development, targeting SGs, 82 RNA modifications or SEs holds therapeutic potential for liver diseases, neurodegeneration, and 83 cancer. Future strategies, including high-throughput screening and rational design of small molecules 84 may enable precision modulation of these regulatory networks.