Future prospects for image-derived input function in molecular imaging quantification with the 7 T MR-BrainPET insert

Frontiers in Neuroscience 2026 Open access

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Authors: Cláudia Régio Brambilla, Julia Hilgers, Usman Khalid, Ninea Anasovi, Tornike Kikacheishvili, Jörg Mauler, Changhoon Choi, Jürgen J Scheins, Nadim Jon Shah, Christoph W. Lerche
DOI: 10.3389/fnins.2025.1725728
Cited by: 0
References: 82

Abstract

Positron emission tomography (PET) and magnetic resonance imaging (MRI) offer complementary information about the human brain in health and disease. The simultaneous 7 T MR-BrainPET insert enables molecular imaging quantification beyond the current limits. Here we present the current status of the field highlighting PET/MR synergies for the image-derived input function (IDIF). We also discuss promising applications that will benefit from these advancements, as well the challenges to be addressed in the near future.

Fields of Study & Subjects

Medical Imaging Techniques and Applications Radiation Detection and Scintillator Technologies Advanced Memory and Neural Computing

Publication details

Journal / source
Frontiers in Neuroscience
Volume
19
Pages
1725728–1725728
Publication date
5 January 2026
Language
EN