MedCSS: a causal self-supervised approach for hierarchical feature consistency in 3D medical imaging

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Authors: Jiang Han, Fusong Wang, Xingchen Shen, F Cao
Cited by: 1
References: 21

Abstract

Medical image analysis plays a crucial role in linking perceptual mechanisms with clinical diagnosis, yet conventional deep learning models often rely on statistical correlations rather than modeling the underlying generative structure, leading to limited robustness in small-sample and cross-domain scenarios. To address this issue, we propose a hierarchical feature consistency framework named "MedCSS" that integrates causal self-supervised learning. Built upon a 3D ResNet backbone, the method aligns intermediate and high-level features through distributional consistency while introducing a coding rate-based causal regularization to suppress non-causal redundancy. Experiments on the MedMNIST3D benchmark demonstrate enhanced feature stability, boundary sensitivity, and generalization across diverse medical structures. Visualization analyses further reveal improved morphological coherence and causal interpretability. This study highlights the potential of causal self-supervision for structurally robust and semantically consistent representation learning in three-dimensional medical imaging.

Fields of Study & Subjects

Generative Adversarial Networks and Image Synthesis Domain Adaptation and Few-Shot Learning Face recognition and analysis

Publication details

Journal / source
Frontiers in Neuroscience
Publisher
Frontiers Media SA
Volume
20
Pages
1739716–1739716
Publication date
16 February 2026
Language
EN