Low vitamin D status and 10-year dementia risk in sensory-impaired adults: a propensity score-matched cohort study

Frontiers in Nutrition 2026 Open access

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Authors: Kuo-Chuan Hung, Hsiu-Lan Weng, Yi-Chen Lai, I-Wen Chen
DOI: 10.3389/fnut.2026.1822195
Cited by: 3
References: 33

Abstract

Background Sensory impairment is a strong modifiable risk factor for dementia; however, whether vitamin D deficiency (VDD) was associated with increased risk in this high-risk group remains unclear. Individuals with vision or hearing impairment are prone to VDD due to reduced sunlight exposure, making this question clinically relevant. Methods From the TriNetX Global Collaborative Network, this retrospective cohort study identified adults aged ≥50 years with documented vision and/or hearing impairment and serum 25-hydroxyvitamin D [25(OH)D] measurement. Patients were classified into VDD group (

Fields of Study & Subjects

Vitamin D Research Studies Nutritional Studies and Diet Parathyroid Disorders and Treatments

Publication details

Journal / source
Frontiers in Nutrition
Publisher
Frontiers Media SA
Volume
13
Pages
1822195–1822195
Publication date
31 March 2026
Language
EN