Clinical and pathological characteristics of patients with colorectal cancer under age stratification

Background: The incidence of early-onset colorectal cancer is increasing. The rate of early diagnosis and screening is low, and the prognosis is poor. This study aims to compare the clinical and pathological characteristics of colorectal cancer patients under age stratification, so as to improve the awareness of prevention in different populations and provide the basis for treatment strategies. Methods: This retrospective cross-sectional study included patients who underwent electronic colonoscopy and were diagnosed with colorectal cancer by pathology in Qilu Hospital of Shandong University from July 2017 to June 2020. Their clinical and pathological data were statistically analyzed according to 50 years groups. Results: 850 patients were included (40 50 years). The proportions of comorbidities (7.5% vs 26.8% vs 55.4%, p=0.006) and medical history were higher (12.5% vs 11.1% vs 17.1%, p=0.163) in the >50 years group; the proportion of family history was higher in the