Ferroptosis: a new dawn in the treatment of acute lymphoblastic leukemia
Abstract
Acute lymphoblastic leukemia poses substantial challenges in therapeutic management. As a novel form of programmed cell death, ferroptosis has emerged as a promising research direction in cancer therapy. Studies have emphasized the pivotal role of ferroptosis in ALL, indicating that targeting this pathway could provide a novel therapeutic strategy. This article systematically reviews the molecular regulatory mechanisms of ferroptosis in ALL and explores its potential clinical applications in the treatment and prognostic evaluation of the disease.
Fields of Study & Subjects
Ferroptosis and cancer prognosis
Clusterin in disease pathology
Acute Lymphoblastic Leukemia research
Publication details
- Journal / source
- Frontiers in Oncology
- Publisher
- Frontiers Media SA
- Volume
- 15
- Pages
- 1669432–1669432
- Publication date
- 9 January 2026
- Language
- EN