Editorial: Exploring epigenetic mechanisms in cancer

provided a scoping review of the genes related to cancer-related fatigue, a significant qualityof-life issue for patients. This contribution, while addressing a different facet of cancer, implicitly underscores the broad systemic impact of the disease, which is often mediated by epigenetic changes that regulate gene expression and cellular function.Taken together, the diverse and innovative findings presented in this article collection place the field's discoveries in a broader context. These articles move beyond descriptive observations to mechanistic investigations, bridging the gap between epigenetic dysregulation and functional outcomes in cancer. The insights gained from this collection not only advance our fundamental understanding of cancer biology but also pave the way for the development of new diagnostic and prognostic markers, as well as novel epigeneticbased therapies (Fig. 1). The Editors would like to extend their sincere gratitude to all the authors and reviewers for their outstanding contributions and dedication to this Research Topic. We are confident that this collection will serve as a valuable resource and catalyst for further exploration in the dynamic and critical fields of cancer epigenetics.