Case Report: Surgical resection combined with chemotherapy for a primary cardiac lymphoma involving right heart structures
Abstract
Primary cardiac lymphoma is a highly rare type of malignant tumor that originates from the lymphoid tissue within the heart or pericardium. Surgical treatment is the primary method for obtaining pathological results and relieving obstructions, and chemotherapy is the main method for disease control. We present a case of a 67-year-old woman diagnosed with primary cardiac lymphoma, presenting with shortness of breath and bilateral lower extremity edema after activity. Multimodality imaging results suggest a primary cardiac lymphoma, which was located in the right atrioventricular groove. Surgical resection of the mass was performed and histopathology confirmed the diagnosis of primary cardiac lymphoma. Based on the genetic results, Pola-R-CHP was used for postoperative chemotherapy. Fortunately, no evidence of recurrence of primary cardiac lymphoma was showed 8 months after surgery. Surgical resection combined with chemotherapy has achieved satisfactory results in the treatment of primary cardiac lymphoma.
Fields of Study & Subjects
Cardiac tumors and thrombi
Pericarditis and Cardiac Tamponade
Lymphoma Diagnosis and Treatment
Publication details
- Journal / source
- Frontiers in Oncology
- Publisher
- Frontiers Media SA
- Volume
- 16
- Pages
- 1732411–1732411
- Publication date
- 20 February 2026
- Language
- EN