Case Report: Surgical resection combined with chemotherapy for a primary cardiac lymphoma involving right heart structures

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Authors: Wei Zhu, Xinying Ren, Hanrui Xiong, M Chen, Boxiang Huang, Bo Peng, Dongliang Lin, Xiaoping Fan
Cited by: 1
References: 18

Abstract

Primary cardiac lymphoma is a highly rare type of malignant tumor that originates from the lymphoid tissue within the heart or pericardium. Surgical treatment is the primary method for obtaining pathological results and relieving obstructions, and chemotherapy is the main method for disease control. We present a case of a 67-year-old woman diagnosed with primary cardiac lymphoma, presenting with shortness of breath and bilateral lower extremity edema after activity. Multimodality imaging results suggest a primary cardiac lymphoma, which was located in the right atrioventricular groove. Surgical resection of the mass was performed and histopathology confirmed the diagnosis of primary cardiac lymphoma. Based on the genetic results, Pola-R-CHP was used for postoperative chemotherapy. Fortunately, no evidence of recurrence of primary cardiac lymphoma was showed 8 months after surgery. Surgical resection combined with chemotherapy has achieved satisfactory results in the treatment of primary cardiac lymphoma.

Fields of Study & Subjects

Cardiac tumors and thrombi Pericarditis and Cardiac Tamponade Lymphoma Diagnosis and Treatment

Publication details

Journal / source
Frontiers in Oncology
Publisher
Frontiers Media SA
Volume
16
Pages
1732411–1732411
Publication date
20 February 2026
Language
EN