Phyllodes-predominant prostatic stromal sarcoma concurrent with prostate adenocarcinoma: a case report and literature review

Read full text
Authors: Hongguang Lian, Wenfeng Feng, Ming Zhang, Yanhua Tian, Wenxin Wu, Jinfeng Cui, Yuan Wang
Cited by: 0
References: 19

Abstract

Prostatic stromal sarcoma (PSS) is a rare malignant mesenchymal tumor originating from the specialized stroma of the prostate. It is a heterogeneous tumor, in which a predominantly phyllodes architecture has been documented only in isolated case reports. The co-occurrence of a phyllodes-predominant PSS and prostate adenocarcinoma (PCA) is even more exceptional. Here, we reported a case of a 52-year-old man with the chief complaint of dysuria for 2 months in 2018. Magnetic resonance imaging (MRI) revealed a mass lesion in the left lobe of the prostate. The patient underwent surgical resection, and the pathological examination revealed PSS with a phyllodes-predominant structure accompanied by PCA. We report this rare case to provide valuable clinical information for clinicians and pathologists and to improve the awareness and diagnostic level of this disease.

Fields of Study & Subjects

Urologic and reproductive health conditions Sarcoma Diagnosis and Treatment Prostate Cancer Treatment and Research

Publication details

Journal / source
Frontiers in Oncology
Volume
16
Pages
1742518–1742518
Publication date
11 February 2026
Language
EN