Wedelolactone, a natural coumestan with multiple pharmacological effects
Abstract
Natural products, especially those from medicinal plants, have been increasingly attractive to researchers. Wedelolactone (WL) is a natural coumestan that was first isolated from Wedelia Chinensis. The past decades have seen an increase in the pharmacological reports on this compound, which show that WL possesses anti-inflammatory, antiviral, antibacterial, antitumor and anti-osteoporosis activities, as well as protective effects on organ damages. This review integrates the recent progresses available on its pharmacological effects both in vitro and in vivo , and highlights its potential uses in multiple diseases.
Fields of Study & Subjects
Plant chemical constituents analysis
Bioactive natural compounds
Sesquiterpenes and Asteraceae Studies
Publication details
- Journal / source
- Frontiers in Pharmacology
- Volume
- 16
- Pages
- 1670032–1670032
- Publication date
- 28 January 2026
- Language
- EN