Effects of mitochondrial gene mutation 8923 (A→G) on inflammatory indicators and blood pressure after acute high-altitude exposure
Abstract
Background In recent years, an increasing number of individuals have traveled to or resided in plateau regions for various reasons. The hypobaric hypoxia characteristics of plateau environments represents a key risk factor for acute mountain sickness (AMS). The pathogenesis of AMS remains incompletely understood. The present study aimed to explore the association between the A8923G point mutation in the mitochondrial MT-ATP6 gene and AMS. Methods We enrolled 84 healthy adult male volunteers who traveled together from the plain (Beijing,
Fields of Study & Subjects
High Altitude and Hypoxia
Pulmonary Hypertension Research and Treatments
Mitochondrial Function and Pathology
Publication details
- Journal / source
- Frontiers in Physiology
- Volume
- 17
- Pages
- 1777284–1777284
- Publication date
- 26 February 2026
- Language
- EN