Analysis of influenza vaccination status and health information sources among middle-aged and older adults with multiple chronic diseases in Zhejiang, China: a cross-sectional study

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Authors: Juan Xie, Xiaotong Yan, Qi Zhang, 杨介者, Xuehai Zhang, Dingming Yao, Jinhang Xu
Cited by: 2
References: 32

Abstract

Background The growing proportion of middle-aged and older adults with multiple chronic diseases, this group faces a high risk of severe complications and death following influenza infection. However, province-level data on influenza vaccine uptake in this vulnerable group are lacking. This study assessed influenza vaccination coverage and identified factors associated with vaccination intention and behavior among multi-morbid patients in Zhejiang Province, China. Method A convenience sampling method was utilized to select the sample. A face-to-face questionnaire survey was conducted among multi-morbid patients aged 50 and above in Zhejiang Province. Chi-square testing and multivariate logistic regression were used to analyze factors that may be associated with influenza. Result Among 2,531 respondents, 1,390 individuals received influenza vaccination, yielding a coverage rate of 54.92%. Multivariate analysis showed age [odds ratio (OR) = 18.239, 95% confidence interval (CI): 11.718, 28.388], occupation [OR = 5.648, 95% CI: 2.935, 10.867], self-rated health status [OR = 3.070, 95% CI: 1.152, 8.179], doctor recommendation [OR = 2.586, 95% CI: 2.099, 3.186] were associated with flu vaccination. The most frequently reported reasons for vaccination were awareness of free-vaccine policies (69.85%), community campaigns highlighting vaccine benefits (54.17%), and medical advice to vaccinate (43.95%). Key reasons for non-vaccination included perceiving oneself as not at risk or vaccination as unnecessary (46.01%), doubts about vaccine effectiveness (23.14%), lack of awareness of the vaccine (22.17%), and concerns about safety or side effects (18.76%). The main sources of vaccine-related information were television (64.24%), doctors (62.62%), and family members (53.30%). Participants aged ≥80 years were more likely to obtain health knowledge from family members (χ 2 = 8.949, p = 0.030). In contrast, participants aged 50–59 years were more likely to rely on WeChat (χ 2 = 208.764, p < 0.001) and TikTok (χ 2 = 191.295, p < 0.001) as sources of health information. Conclusion The influenza vaccination rate among middle-aged and older adults with multiple chronic diseases in Zhejiang Province remains notably low. To enhance the willingness of this group to receive the influenza vaccine, it is essential to consider both factors that promote or hinder vaccination, along with the implementation of targeted communication strategies to effectively enhancing their willingness to receive the influenza vaccine.

Fields of Study & Subjects

Influenza Virus Research Studies Vaccine Coverage and Hesitancy Immune responses and vaccinations

Publication details

Journal / source
Frontiers in Public Health
Publisher
Frontiers Media SA
Volume
13
Pages
1719412–1719412
Publication date
12 January 2026
Language
EN